Polyhexamethylene biguanide in the treatment of Acanthamoeba keratitis
نویسندگان
چکیده
منابع مشابه
Benefit of polyhexamethylene biguanide in Fusarium keratitis.
PURPOSE To report a series of 3 patients with soft contact lens-related Fusarium keratitis. Two of them were treated with the antiamoebic polyhexamethylene biguanide 0.02% (PHMB) in combination with antifungal drugs, and 1 patient was treated with PHMB as sole antifungal regimen. METHODS Chart review of 3 patients treated with PHMB in Fusarium keratitis. Two of them were refractory to the com...
متن کاملDouble-Biguanide Therapy for Resistant Acanthamoeba Keratitis
AIMS To report the clinical and diagnostic findings of a patient with Acanthamoeba keratitis resistant to both polyhexamethylene biguanide (PHMB)-hexamidine and chlorhexidine-hexamidine treatment. METHODS Slit-lamp biomicroscopy, corneal cell scraping and histopathology were performed on a 39-year-old woman presenting with corneal ulcer in her left eye. RESULTS The patient was successfully ...
متن کاملclinical outcomes in acanthamoeba keratitis treated with polyhexamethylene biguanide as monotherapy
purpose: to assess the efficacy of polyhexamethylene biguanide (phmb) in treating acanthamoeba keratitis (ak) and also to identify related factors affecting final visual outcome in ak patients treated with phmb methods: in these interventional case series study, 27 eyes of 25 patients with ak received phmb 0.02% and divided into two groups according to the final visual acuity (va) va equal to o...
متن کاملToxicological assessment of polyhexamethylene biguanide for water treatment
Polyhexamethylene biguanide (PHMB) is an antiseptic with antiviral and antibacterial properties used in a variety of products including wound care dressings, contact lens cleaning solutions, perioperative cleansing products, and swimming pool cleaners. There are regulatory concerns with regard to its safety in humans for water treatment. We decided to assess the safety of this chemical in Sprag...
متن کاملPolyhexamethylene biguanide and calcineurin inhibitors as novel antifungal treatments for Aspergillus keratitis.
PURPOSE To establish polyhexamethylene biguanide (PHMB) as an effective treatment for Aspergillus keratitis in a novel murine model. To determine the ability of the calcineurin inhibitors tacrolimus (FK506) and cyclosporine A (CSA) to enhance the activity of PHMB, amphotericin B (AMB), and voriconazole (VCZ) against Aspergillus keratitis. METHODS IN VITRO STUDIES Broth antifungal susceptib...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Australian and New Zealand Journal of Ophthalmology
سال: 1993
ISSN: 0814-9763,1440-1606
DOI: 10.1111/j.1442-9071.1993.tb00971.x